Extract of grape leaf
Grape seed dry
CAS: 84929-27-1
Molecular Formula: C32H30O11
Extract of grape leaf - Names and Identifiers
Extract of grape leaf - Physico-chemical Properties
| Molecular Formula | C32H30O11 |
| Molar Mass | 590.574 |
| Density | 0.961g/cm3 at 20℃ |
| Vapor Presure | 0.003Pa at 60℃ |
| Appearance | Solid:particulate/powder |
| Storage Condition | Inert atmosphere,Room Temperature |
Extract of grape leaf - Reference
| Reference Show more | 1. [IF=9.147] Yuntao Wang et al."Chitin microspheres: A fascinating material with high loading capacity of anthocyanins for colon specific delivery."Food Hydrocolloid. 2017 Feb;63:293 2. [IF=7.514] Meng-Ning Li et al."A modified data filtering strategy for targeted characterization of polymers in complex matrixes using drift tube ion mobility-mass spectrometry: Application to analysis of procyanidins in the grape seed extracts."Food Chem. 2020 Aug;3 3. [IF=4.192] Haibo Pan et al."Assembly of Oil-Based Microcapsules Coated with Proanthocyanidins as a Novel Carrier for Hydrophobic Active Compounds."J Agr Food Chem. 2020;68(20):5715–5722 4. [IF=3.423] Yangyang Guo et al."Fabrication of functional nanofibril film from biodegradable konjac glucomannan and polyethylene oxide via electrospinning method."Mater Lett. 2022 Jan;307:131066 5. [IF=4.412] Ziqi Qian et al."Analysis of Proanthocyanidins in Plant Materials Using Hydrophilic Interaction HPLC-QTOF-MS."MOLECULES. 2022 Jan;27(9):2684 |
Extract of grape leaf - Reference Information
| Plant Source: | grape seed |
| FEMA | 4045 | GRAPE SEED EXTRACT |
| LogP | 6.5 at 25℃ and pH5-6 |
| trait | the grape seed extract was brown-red powder. |
| medicinal value of grape seed | grape seed has the advantages of "invigorating qi and blood, strengthening bones, improving urination, treating deficiency of qi and blood, lung deficiency Cough, palpitation, night sweats, rheumatism, gonorrhea, edema and other effects, modern research shows that grape seed extract of procyanidins with antioxidant and lower cholesterol levels, is a potential natural antioxidant, can be used for the prevention and treatment of high cholesterol, atherosclerosis, cataract, gastric ulcer, intestinal adenocarcinoma, Ehrlich ascites cancer. The main pharmacological effects are as follows: 1, antioxidant effect: the polyphenols in grape seed extract include phenolic hydroxyl groups of proanthocyanidins and gallic acid, which provide hydrogen atoms and have specific and powerful antioxidant effect. The ability to neutralize iron ions and oxygen of Aggression lipid is 15-25 times that of VB, and its free radical scavenging effect is stronger than that of antioxidants such as VC.VE. 2, anti radiation effect: can inhibit the radiation induced lipid peroxidation. 3, anti-inflammatory effect: the main component is proanthocyanidins, and its antioxidant activity can inhibit the synthesis and release of inflammatory factors such as histamine, serotonin, prostaglandin and leukotriene, inhibition of basophils and mast cell release granules, but also inhibit the activity of histamine decarboxylase, limit the role of hyaluronidase. 4, prevention of cataract: the main component of the prevention of cataract is catechin; Grape seed extract can improve the visual acuity of patients with Myopic retinal non-inflammatory changes, can improve eye fatigue. 5, anti-cancer effect: it has cytotoxicity on MCF-7 human breast tumor cells, A- 427 human lung cancer cells and CRL1739 human gastric adenocarcinoma cells, and can prevent the carcinogenic effect of intestinal chemical carcinogens. 6, anti atherosclerosis effect: 2.5% grape seed extract of food, can reduce the experimental animal serum cholesterol ester peroxide levels, but also reduce the low density lipoprotein to fight atherosclerosis. Can improve blood rheology and platelet aggregation. 7, cholesterol-lowering effect: gallate tannins can reduce plasma total cholesterol, triglyceride, low density cholesterol and very low density cholesterol levels, and increase high density cholesterol levels. 8, anti-ulcer effect: oligomeric proanthocyanidins in grape seed extract can protect gastric mucosa damage, and proanthocyanidins have the effect of scavenging free radicals on the gastric surface and protecting the gastric wall. 9, anti mutation effect: can reduce the incidence of mitochondrial mutation and nuclear mutation. |
| Introduction | grape seed extract is a kind of polyphenols extracted from grape seed, it is an edible product. It is a powerful antioxidant, a highly effective free radical scavenger. For food supplements, health food and cosmetics. |
| plant extract | grape seed extract is a plant extract, the main component is proanthocyanidins, it is a new efficient natural antioxidant extracted from grape seeds, which cannot be synthesized in the human body. It is one of the most efficient antioxidants of plant origin found so far, the antioxidant effect of grape seed extract is 50 times stronger than vitamin E and 20 times stronger than vitamin C. It can effectively remove excess free radicals in the human body, with super anti-aging and enhance the role of immunity, known as the main efficacy of anti-inflammatory, anti-histamine, anti-allergic, anti-allergen, antioxidant, anti-fatigue, enhance physical fitness, improve sub-health state anti-aging, improve irritability, dizziness Fatigue, memory loss symptoms, beauty, promote blood circulation. In Europe, grape seed is known as "oral skin cosmetics". Grape seed is a natural sun covering, can prevent ultraviolet rays against the skin. The sun can kill 50% of human skin cells; But if you take grape seeds to protect, about 85% of skin cells can survive death. Because the proanthocyanidins (OPC) in grape seeds have a special affinity for the collagen and elastic fibers of the skin, they can be protected from damage. Grape seed extract as the main functional component of oriental female cosmetics, by inhibiting the activity of tyrosinase, scavenging free radicals to reduce melanin deposition and dermatitis, has a astringent effect, tightening the skin, Prevent early appearance of skin wrinkles, long-term use can make the skin smooth, elastic, with the role of beauty. |
| pharmacological effects | grape seed extract has antioxidant, antimutagenic, anticancer, antiviral, anti-inflammatory, anti-ulcer, reduce the role of cholesterol, clinical for the prevention and treatment of high cholesterol, atherosclerosis, gastric ulcer, etc., as food additives, cosmetics, health products and beverages and other raw materials. Grape seed extract is one of the most efficient antioxidants of plant origin found so far. In vivo and in vitro tests show that the antioxidant effect of grape seed extract is 30-50 times that of vitamin C and vitamin E. Super Antioxidant efficiency has a strong effect on scavenging free radicals and improving human immunity. Free radicals are one of the important causes of aging and many diseases. It is estimated that about 80%-90% of aging and degenerative diseases are related to free radicals, including cancer, Alzheimer's disease, Parkinson's disease, skin |
| approval date | 2012-11-12 |
| Announcement No. | |
| announcement title | Announcement of Ministry of Health on approval of four new resource foods such as Chlorella pyrenoidosa |
| formulation method | 1. Weighing the prescription amount of grape seed extract crushing, 100 mesh sieve, standby; 2. Weigh the prescription amount of maltodextrin and xylitol anhydride monooleate, grinding, grinding while adding the grape seed extract of Step 1 to continue grinding, the main grinding; 3. Grinding the starch by parts by weight, the microcrystalline cellulose by 55% parts by weight, and the carrageenan by parts by weight to obtain a subgrind; 4. The main abrasive and the sub-abrasive are mixed uniformly and granulated to obtain coarse particles; 5. Passing the coarse particles through a 100 mesh screen to obtain fine particles; 6. The high-purity grape seed extract tablet of the present invention is obtained by uniformly mixing the silica, magnesium stearate and the remaining portion of microcrystalline cellulose with the fine particles and compressing the tablet. |
Last Update：2024-04-09 15:16:53
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